IRIS™ Polymeric SPE
Polymeric based SPE product line available in many configurations with 25-35 micron particle sizes and various surface chemistry for ion-exchange, hydrophilic and hydrophobic interaction.

Advantages of Polymeric SPE
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Excellent recovery - highly retentive nature of polymeric phases
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Absence of residual silanol groups
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High surface area that results in higher analyte capacity compared to silica based SPE
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Absence of leachables
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Inert to a wide array of solvents and pH range
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Reduced resin volumes for improved detection limits
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Resistant to dewetting
Polymeric SPE Phases available:
IRIS N (Neutral) RP-HLB: Polyamide SPE Phase 
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Polyamide sorbent - HLB phase
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Pore size: 80Å
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Surface area: ~500m2/g
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Available in 25-35µm or 55-65µm particle sizes
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Available in various cartridge sizes and 96-well plates
IRIS PLUS (100% DVB): Highly retentive reverse phase SPE 
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100% Divinylbenzene (DVB) phase
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Features reduced swelling and increased retention over (PS-DVB) phases
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Plus – Most hydrophobic for highest retention
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Excellent for environmental samples.
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Available in 25-35µm or 55-65µm particle sizes
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Available in various cartridge sizes and 96 well plates
Example of applications:
Theobromine, Theophylline, Caffeine
Polycyclic aromatic hydrocarbons (PAHs)
IRIS MCX (Mixed Mode Strong Cation Exchange)
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Sulfonated hydrophilic on DVB support
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Pore size: 80Å
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Ion-Exchange capacity: ~1 meq/g
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pKa <1
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Available in 25-35µm or 55-65µm particle sizes
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Available in various cartridge sizes and 96-well plates
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Secondary amine on DVB support
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Pore size: 80Å
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Ion-Exchange capacity: ~1 meq/g
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pKa ~7
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Available in 25-35µm or 55-65µm particle sizes
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Available in various cartridge sizes and 96-well plates
Example of applications:
Ketoprofen
Nitro-L-Tyrosine, Iodo-L-Tyrosine, N-Acetyl-L-Tyrosine